Much has changed since we last published our list of the 50 most iconic cocktails in San Francisco, back in 2019 before the pandemic struck. Some of SF's most beloved bars closed permanently (RIP Bar Agricole, The Saratoga), some remain shuttered temporarily (Slanted Door, P.C.H.), and several new ones have opened (Bar Iris, Mothership). The city and this list, which represents the most notable adult beverages it has to offer, have experienced a big shuffle, but that’s all the more reason to get out on the town to explore new venues and revisit the old standards you’ve likely been missing over the last couple years.